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Should Collagen Be Taken on an Empty Stomach?

Quick Answer: It does not matter if you take collagen on an empty stomach or with a meal. Collagen peptides are absorbed through the intestines and then into the bloodstream regardless of when you take them.

Collagen supplements have become popular for their potential benefits to skin, hair, nails, and joints. However, there is much debate about the best time to take collagen and whether it should be taken on an empty stomach. This report explores various perspectives and scientific insights on this topic.

Collagen Absorption Myths

Many believe taking collagen on an empty stomach enhances absorption. The theory suggests that stomach acid, more active when the stomach is empty, better digests collagen. However, this is a myth. Stomach acid is always present and active, regardless of food intake. The majority of protein digestion, including collagen, occurs in the miniature intestine, not the stomach. Therefore, whether you take collagen on an empty stomach or with food, the absorption remains the same. According to a study, the body absorbs collagen peptides effectively regardless of stomach contents.

Timing and Effectiveness

The timing of collagen intake does not significantly impact its effectiveness. Some suggest taking collagen in the morning on an empty stomach, while others recommend taking it at night to align with the body’s natural repair processes during sleep. However, there is no scientific evidence supporting these claims. The best time to take collagen is when it fits your routine, ensuring consistent use. Consistency is key to reaping the benefits of collagen supplements, as highlighted by Brightcore Nutrition.

Collagen and Vitamin C

Vitamin C is essential for collagen synthesis in the body. Some manufacturers add vitamin C to collagen supplements or recommend taking them together. While vitamin C aids collagen production, it is not necessary to consume it simultaneously with collagen supplements. Ensuring adequate vitamin C intake through diet or supplements can support collagen synthesis. According to Naked Nutrition, a diet rich in fruits and vegetables provides sufficient vitamin C for collagen production.

Collagen Types and Sources

Collagen supplements come from various sources, including bovine, marine, and poultry. Each type has different amino acid profiles, but all provide similar benefits. Hydrolyzed collagen, or collagen peptides, is the most effective form as it is broken down into miniatureer molecules for easier absorption. Both fish and bovine collagen contain Type 1 collagen, essential for skin, hair, and nails. Fish collagen has miniatureer amino acids, potentially making it easier to absorb, but no studies conclusively compare the absorption rates of different collagen sources. ShopHope suggests choosing high-quality, hydrolyzed collagen for best results.

Potential Side Effects

Collagen supplements are generally safe, but some people may experience mild side effects like bloating, diarrhea, or constipation. These effects are usually due to the body’s adjustment to the supplement or intolerance to certain ingredients. Allergic reactions can occur, especially if the collagen is derived from seafood or eggs. It is crucial to consult a healthcare provider before starting any new supplement, especially if you have existing health conditions or allergies. Bustle highlights the importance of monitoring for any adverse reactions.

Collagen and Fasting

Taking collagen during quicking periods, such as intermittent quicking, is safe and can be beneficial. Collagen does not break a quick and can support joint health, skin hydration, and muscle maintenance during quicking. Marine collagen is particularly recommended during quicking for its high absorption rate. According to Yonboon, consuming collagen during quicking can enhance gut health and support overall well-being.

Practical Tips for Collagen Intake

Incorporating collagen into your daily routine can be effortless and flexible. Collagen powders can be mixed into coffee, smoothies, or water, while capsules offer a convenient option for on-the-go use. The key is to find a method that fits your lifestyle and ensures consistent intake. Whether you prefer taking collagen in the morning, midday, or at night, the most crucial factor is regular consumption. Vital Proteins emphasizes the importance of integrating collagen into your routine in a way that works best for you.

Key Takeaways

  • Collagen absorption is not affected by whether you take it on an empty stomach or with food.
  • The timing of collagen intake does not significantly impact its effectiveness.
  • Vitamin C supports collagen synthesis but does not need to be taken simultaneously with collagen.
  • Hydrolyzed collagen is the most effective form for absorption.
  • Collagen supplements are generally safe but may cause mild side effects in some individuals.
  • Taking collagen during quicking is safe and can support overall health.
  • Consistent intake is key to reaping the benefits of collagen supplements.


Collagen supplements offer numerous benefits for skin, hair, nails, and joints. The timing of collagen intake and whether it is taken on an empty stomach do not significantly impact its effectiveness. Consistency and choosing a high-quality, hydrolyzed collagen supplement are crucial. Incorporating collagen into your daily routine in a way that fits your lifestyle ensures you can enjoy its benefits. Personal preferences and individual responses to supplements vary, so finding what works best for you is essential.