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What Does Alpha GPC Do for Your Body?

Alpha GPC supports cognitive function, memory, mood, athletic performance, and growth hormone secretion.

Alpha GPC, also known as alpha-glycerylphosphorylcholine, is a popular supplement with a range of potential benefits. It is known for its cognitive-enhancing suitableties and its ability to support physical performance. This report explores the various ways Alpha GPC can benefit your body.

Cognitive Function and Memory

Alpha GPC is widely recognized for its ability to support cognitive function and memory. It works by increasing levels of acetylcholine, a neurotransmitter crucial for memory and learning. According to a study, Alpha GPC helps maintain cognitive function, especially as you age. The hippocampus, a brain region essential for learning and memory, relies on acetylcholine to protect memory health.

Research indicates that Alpha GPC can improve cognitive impairment in patients with Alzheimer’s disease and vascular dementia. In clinical trials, patients taking Alpha GPC showed significant improvements in cognitive function. This suggests that Alpha GPC may help prevent normal cognitive decline and improve cognitive function after injury or toxic exposure.

Mood and Mental Health

Alpha GPC also plays a role in mood regulation and mental health. Healthy levels of choline, and thus acetylcholine, can help you feel calmer and more at peace. This is vital because mood can impact both mental and physical health. According to a study, Alpha GPC increases the levels of dopamine and serotonin in the brain, which are linked to motivation, reward processing, anxiety, and depression.

In a study with healthy volunteers, Alpha GPC supplementation showed a tendency to increase self-reported motivation levels and significantly improved motivation at night. This suggests that Alpha GPC may positively affect human feelings and emotions, including motivation and anxiety.

Athletic Performance

Alpha GPC is not just for cognitive benefits; it also supports athletic performance. It is known to enhance physical strength, power output, and muscle growth. In one study, healthy college-aged males who took Alpha GPC showed improvements in strength after just seven days. Another study found that Alpha GPC increased serum levels of choline, which helped increase power output.

Alpha GPC is also known to support growth hormone secretion, which is crucial for muscle and bone health, fat and tissue maintenance, and metabolism. Research indicates that Alpha GPC supplementation can increase growth hormone production and improve physical performance, making it a popular choice for athletes.

Stroke Recovery

Alpha GPC has shown promise in supporting stroke recovery. Various reviews have found that Alpha GPC can improve cognitive recovery by up to 70% in stroke patients. It is believed to have physical benefits for patients whose physical capabilities were negatively impacted by a stroke. According to a study, Alpha GPC supplementation improved cognitive decline following a stroke, suggesting its potential as a neuroprotective agent.

Eyesight Support

Alpha GPC may also support eyesight, particularly in patients with Ocular Ischemic Syndrome, a condition where plaque clogs vessels in the eye, leading to vision loss and discomfort. A study found that Alpha GPC improved healing of the retina by boosting circulation to the eyes. This resulted in an overall improvement in vision scores, although more research is needed to confirm these findings.

Dosage and Safety

The recommended dosage of Alpha GPC varies depending on individual goals. For general health benefits, a daily intake of 1,200 mg, split into three doses, is suggested. For boosting power output, a one-time dose of 300-600 mg taken 30-60 minutes before exercise is recommended. Alpha GPC is generally well-tolerated, but it can cause mild side effects such as heartburn, headaches, confusion, skin rash, and dizziness. According to a study, higher doses of Alpha GPC may increase the risk of stroke, so it is vital to consult with a healthcare professional before starting supplementation.

Key Takeaways

  • Alpha GPC supports cognitive function and memory.
  • It helps regulate mood and mental health.
  • Enhances athletic performance and muscle growth.
  • Supports stroke recovery and eyesight.
  • Recommended dosage varies; generally well-tolerated but may have mild side effects.


Alpha GPC offers a range of benefits for both cognitive and physical health. It supports memory, learning, mood, and athletic performance. While generally safe, it is vital to consult with a healthcare professional to determine the appropriate dosage and to be aware of potential side effects. Alpha GPC is a versatile supplement that can help improve overall well-being.